Yazar "Bagirici, Faruk" için listeleme
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Alpha-Tocopherol Decreases Iron-Induced Hippocampal and Nigral Neuron Loss
Bostanci, M. Oemer; Bas, Orhan; Bagirici, Faruk (Springer/Plenum Publishers, 2010)There are many studies about iron-induced neuronal hyperactivity and oxidative stress. Some reports also showed that iron levels rise in the brain in some neurodegenerative diseases such as Parkinson's (PD) and Alzheimer's ... -
Anticonvulsant effect of carnosine on penicillin-induced epileptiform activity in rats
Kozan, Ramazan; Sefil, Fatih; Bagirici, Faruk (Elsevier Science Bv, 2008)Carnosine is a compound of naturally-occurring dipeptide that synthesized by the carnosine synthetase from beta-alanine and L-histidine. Recent reports claim that carnosine plays an important role in the control of epilepsy ... -
Anticonvulsive effects of carbenoxolone on penicillin-induced epileptiform activity: An in vivo study
Bostanci, M. Omer; Bagirici, Faruk (Pergamon-Elsevier Science Ltd, 2007)Epilepsy is an important problem in neurological disorders. Recent studies claimed that gap junctions have a critical role in epileptic neuronal events. The aim of present study is to investigate the effects of gap junction ... -
Anticonvulsive effects of nimodipine on penicillin-induced epileptiform activity
Bagirici, Faruk; Bostanci, M. Omer (Nencki Inst Experimental Biology, 2006)The common features of all types of epilepsy are synchronized and uncontrolled discharges of nerve cell assemblies. It is believed that calcium ions play an important role in the generation of epileptic activity. Excessive ... -
Anticonvulsive effects of quinine on penicillin-induced epileptiform activity: An in vivo study
Bostanci, M. Oemer; Bagirici, Faruk (W B Saunders Co Ltd, 2007)Epilepsy is an important problem in neurological disorders. The common features of all types of epilepsy are the synchronized and uncontrolled discharges of nerve cell assemblies. Recent studies claimed that gap junctions ... -
Blocking of L-type calcium channels protects hippocampal and nigral neurons against iron neurotoxicity the role of L-type calcium channels in iron-induced neurotoxicity
Bostanci, M. Omer; Bagirici, Faruk (Informa Healthcare, 2013)Iron plays an important role in maintaining normal brain function. However, iron overload and enhanced hydroxyl radical formation have been implicated as the causative factors of some neurodegenerative disorders such as ... -
Effect of levetiracetam on penicillin induced epileptic activity in rats
Arik, Aliye Erguvan; Bagirici, Faruk; Sefil, Fatih; Marangoz, Cafer (Nencki Inst Experimental Biology, 2014)The aim of this study was to investigate the effects of levetiracetam (LEV) on penicillin- induced epileptiform activity in rats. Penicillin was applied intracerebroventricularly (icy) at a dose of 500 IU to induce ... -
The Effect of Neuronal Nitric Oxide Synthase Inhibitor 7-Nitroindazole on the Cell Death Induced by Zinc Administration in the Brain of Rats
Gokce, M. Fatih; Bagirici, Faruk; Demir, Serif; Bostanci, M. Omer; Guven, Aysel (Tubitak Scientific & Technical Research Council Turkey, 2009)Aim: To evaluate the effect of the neuronal nitric oxide synthase (nNOS) inhibitor 7-nitroindazole (7-Nl) on hippocampal cell loss induced by zinc hemisulfate salt (ZnSO4-7H2O) treatment. Materials and Methods: Rats were ... -
The Effects of Nitric Oxide Synthesis Inhibitors on Iron-Induced Nigral Neurotoxicity
Bostanci, M. Omer; Bas, Orhan; Bagirici, Faruk (Springer Tokyo, 2009)… -
Influence of carbenoxolone on the anticonvulsant efficacy of phenytoin in pentylenetetrazole kindled rats
Sefil, Fatih; Bagirici, Faruk; Acar, M. Dilek; Marangoz, Cafer (Nencki Inst Experimental Biology, 2012)Abnormal synchronized neuronal discharges mediated by gap junctions have an important role in epileptic seizures. The analysis of anticonvulsant drugs acting on gap junctions is still a priority in epilepsy research. ... -
Inhibition of neuronal nitric oxide synthase prevents iron-induced cerebellar Purkinje cell loss in the rat
Gulturk, Sefa; Kozan, Ramazan; Bostanci, M. Omer; Sefil, Fatih; Bagirici, Faruk (Nencki Inst Experimental Biology, 2008)Iron plays an important role in maintaining normal. brain function. However, in many neurodegenerative diseases abnormal iron accumulation in specific brain regions has been consistently reported. In this study, we ... -
Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy
Sefil, Fatih; Arik, Aliye E.; Acar, Meryem D.; Bostanci, Mehmet O.; Bagirici, Faruk; Kozan, Ramazan (E-Century Publishing Corp, 2015)Gap junctions play an important role in the synchronized neuronal discharges. The main reason of the epileptic seizures is disruption of this synchronization. Therefore, the aim of the present study is to explore the ... -
Iron-Induced Cerebellar Purkinje Cell Loss Is Ameliorated by Flunarizine
Kozan, Ramazan; Bostanci, M. Oemer; Nacar, Tuncer; Aslan, Ali; Bagirici, Faruk (Tubitak Scientific & Technical Research Council Turkey, 2009)Aim: In this study, we investigated the effect of intracerebroventricular-injected iron neurotoxicity on the total number of cerebellar Purkiinje cells in rats and the possible neuroprotective effect of flunarizine, a ... -
Neuroprotection by 7-nitroindazole against iron-induced hippocampal neurotoxicity
Bostanci, M. Omer; Bagirici, Faruk (Springer/Plenum Publishers, 2007)(1) Iron plays an important role in maintaining normal brain function. In some neurodegenerative disorders including Parkinson's and Alzheimer's disease, iron levels rise in the brain. It is known that higher iron levels ... -
Neuroprotective effect of aminoguanidine on iron-induced neurotoxicity
Bostanci, M. Omer; Bagirici, Faruk (Pergamon-Elsevier Science Ltd, 2008)Iron is a commonly used metal to induce neuronal hyperactivity and oxidative stress. Iron levels rise in the brain in some neurodegenerative disorders such as Parkinson's and Alzheimer's diseases. A body of evidence indicates ... -
Nitric oxide synthesis inhibition attenuates iron-induced neurotoxicity: A stereological study
Bostanci, M. Oemer; Bagirici, Faruk (Elsevier Science Bv, 2008)Iron overload and enhanced hydroxyl radical formation have been implicated as the causative factors of some neurodegenerative disorders. Therefore, iron is commonly used as a metal to induce neuronal hyperactivity and ... -
Quercetin Decreased Penicillin-induced Epileptiform Activity in Rats
Baysal, Burhanettin; Ucar, Durmus; Bagirici, Faruk (Wiley-Blackwell, 2016)… -
Role of nitric oxide synthesis inhibitors in iron-induced nigral neurotoxicity: A mechanistic exploration
Bostanci, M. Omer; Bagirici, Faruk; Bas, Orhan (Taylor & Francis Ltd, 2008)In the central nervous system, nitric oxide (NO) has been suggested to be a cell-to-cell signaling molecule that regulates guanylyl cyclase, aconitase, and iron regulatory protein. NO is also one of the substances that is ...
