Yazar "Bilge, SS" için listeleme
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Anxiolytic-like profile of propofol, a general anesthetic, in the plus-maze test in mice
The present study was performed to investigate the effect of propofol on anxiety using the elevated plus-maze test. Groups of mice received propofol (20, 40, 60 mg/kg) or diazepam (2 mg/ kg), caffeine (3 0 mg/kg), L-arginine ... -
Effect of sildenafil on anxiety in the plus-maze test in mice
Kurt, M; Bilge, SS; Aksoz, E; Kukula, O; Celik, S; Kesim, Y (Polish Acad Sciences Inst Pharmacology, 2004)Several studies have shown a role of nitric oxide/cyclic guanosine monophosphate signaling pathway in the regulation of anxiety. The effects of the phosphodiesterase (PDE) 5 inhibitors on anxiety are not fully understood. ... -
Possible role of sildenafil in inhibiting rat vas deferens contractions by influencing the purinergic system
Aim: To evaluate the effect of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-selective type 5 phosphodiesterase, on isolated rat vas deferens and its connections with the purinergic system. ... -
The role of nitrergic system in lidocaine-induced convulsion in the mouse
The effects of N-nitro-L-arginine-methyl ester (L-NAME) a nitric oxide (NO) synthase inhibitor and L-arginine, a NO precursor, were investigated on lidocaine-induced convulsions. In the first experiment, four groups of ...