Yazar "Bilge, Sirri" için listeleme
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Chronic treatment with fluoxetine and sertraline prevents forced swimming test-induced hypercontractility of rat detrusor muscle
Bilge, Sirri; Bozkurt, Ayhan; Basl, Duygu B.; Aksoz, Elif; Savli, Evren; Ilkaya, Fatih; Kesim, Yuksel (Polish Acad Sciences Inst Pharmacology, 2008)Serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibitors represent important targets for the development of new treatments for detrusor overactivity and urinary incontinence. The present study was undertaken to investigate ... -
Effect of prenatal levetiracetam exposure on motor and cognitive functions of rat offspring
Ozyurek, Hamit; Bozkurt, Ayhan; Bilge, Sirri; Ciftcioglu, Engin; Ilkaya, Fatih; Bas, Duygu Belkis (Elsevier Science Bv, 2010)Purpose. We aimed to establish the physical, motor, and cognitive teratogenic effect of levetiracetam exposure throughout pregnancy in rats. Methods. Thirty-two Sprague Dawley pregnant female rats were divided into four ... -
Evaluation of Antinociceptive and Neurotoxic Effects of Intrathecal Dexmedetomidine in Rats
Isguzar, Ozgu; Baris, Sibel; Bozkurt, Ayhan; Can, Bilge; Bilge, Sirri; Ture, Hatice (Galenos Yayincilik, 2012)Objective: Dexmedetomidine has been reported to produce analgesia after intrathecal administration. In the present study the alpha 2-adrenoceptor agonist dexmedetomidine was evaluated for its potential spinal neurotoxic ... -
Evaluation of Postoperative Anti-nociceptive Efficacy of Intrathecal Dexketoprofen in Rats
Er, Birol Muhammet; Kocamanoglu, Ismail Serhat; Bozkurt, Ayhan; Bilge, Sirri; Cetinoglu, Erhan Cetin (Aves, 2016)Background: Some studies have suggested that the intrathecal use of cyclooxygenase enzyme inhibitors provides an anti-nociceptive effect. Therefore, the occurrence of side effects seen in systemic usage can be eliminated. ... -
Protective effect of vitamin A on ARA-C induced intestinal damage in mice
Elli, Murat; Aydin, Oguz; Bilge, Sirri; Bozkurt, Ayhan; Dagdemir, Ayhan; Pinarli, Faruk Guclu; Acar, Sabri (Sage Publications Ltd, 2009)Background. Cytarabine (ARA-C) has been used for many years in the treatment of patients with leukemia and lymphoma. Gastrointestinal ulceration and mucositis are two of the well-known side effects of ARA-C. We set out to ... -
The role of heart-type fatty acid-binding protein in the evaluation of carbon monoxide poisoning in rats
Yardan, Turker; Meric, Murat; Bozkurt, Ayhan; Bilge, Sirri; Bas, Duygu Belkis; Bedir, Abdulkerim; Baydin, Ahmet (Sage Publications Ltd, 2011)Acute carbon monoxide (CO) poisoning can cause early and persistent damages in tissues sensitive to hypoxia. This study investigated serum heart-type fatty acid-binding protein (H-FABP) levels as a biomarker of acute CO ... -
Time Course of Serum S100B Protein and Neuron-Specific Enolase Levels of a Single Dose of Chlorpyrifos in Rats
Bozkurt, Ayhan; Yardan, Turker; Ciftcioglu, Engin; Baydin, Ahmet; Hakligor, Aylin; Bitigic, Medine; Bilge, Sirri (Wiley, 2010)Organophosphate (OP) compounds are a large class of chemicals, many of which are used as pesticides. It is suggested that OPs specifically affect glia and neurons. Effects of acute exposure to chlorpyrifos (CPF), which is ...