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Synthesis of 3,4-dihydroxypyrrolidine-2,5-dione and 3,5-dihydroxybenzoic acid derivatives and evaluation of the carbonic anhydrase I and II inhibition

Arslan, Mehmet; Senturk, Murat; Fidan, Ismail; Talaz, Oktay; Ekinci, Deniz; Cosgun, Sedat; Supuran, Claudiu T. (Taylor & Francis Ltd, 2015)

The inhibition of two human cytosolic carbonic anhydrase (hCA, EC 4.2.1.1) isozymes I and II, with some 3,4-dihydroxypyrrolidine-2,5-dione and 3,5-dihydroxybenzoic acid derivatives, were investigated by using the esterase ...