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Functionalized imidazolium and benzimidazolium salts as paraoxonase 1 inhibitors: Synthesis, characterization and molecular docking studies
Karatas, Mert Olgun; Uslu, Harun; Alici, Bulent; Gokce, Basak; Gencer, Nahit; Arslan, Oktay; Özdemir, Namık (Pergamon-Elsevier Science Ltd, 2016)Paraoxonase (PON) is a key enzyme in metabolism of living organisms and decreased activity of PON1 was acknowledged as a risk for atherosclerosis and organophosphate toxicity. The present study describes the synthesis, ... -
Inhibition of paraoxonase 1 by coumarin-substituted N-heterocyclic carbene silver(I), ruthenium(II) and palladium(II) complexes
Karatas, Mert Olgun; Calgin, Gamze; Alici, Bulent; Gokce, Basak; Gencer, Nahit; Tok, Tugba Taskin; Özdemir, Namık (Wiley, 2019)We synthesized three coumarin-substituted benzimidazolium chlorides and their silver(I), ruthenium(II) and palladium(II) N-heterocyclic carbene (NHC) complexes. All compounds were characterized using appropriate spectroscopic ...
