Yazar "Gunaydin, Caner" için listeleme
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Effects of agomelatine in rotenone-induced Parkinson's disease in rats
Gunaydin, Caner; Avci, Bahattin; Bozkurt, Ayhan; Onger, Mehmet Emin; Balci, Hakan; Bilge, S. Sirri (Elsevier Ireland Ltd, 2019)The effects of melatonin and melatonin analogs in experimental Parkinson's disease (PD) models remain controversial. Agomelatine, a novel analog of melatonin, is both agonists for melatonin-1 and melatonin-2 receptors and ... -
Effects of Nonsteroidal Anti-Inflammatory Drugs at the Molecular Level
Gunaydin, Caner; Bilge, S. Sirri (Aves, 2018)Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for their anti-inflammatory, analgesic, and antipyretic effects. NSAIDs generally work by blocking the production of prostaglandins (PGs) through the inhibition ... -
The false-positive responses of analgesic drugs to the intradermal serotonin- and compound 48/80-induced scratches as an animal model of itch
Ilkaya, Fatih; Yesilyurt, Ozgur; Seyrek, Melik; Gunduz, Ozgur; Ide, Tayfun; Akar, Ahmet; Gunaydin, Caner (Nencki Inst Experimental Biology, 2016)Intradermal injection of pruritogens such as serotonin, histamine and compound 48/80 into the skin and then, the evaluation of the scratching behavior is the commonly used animal model to advance pruritic research and drug ... -
Proconvulsant effect of trans-cinnamaldehyde in pentylenetetrazole-induced kindling model of epilepsy: the role of TRPA1 channels
Gunaydin, Caner; Arslan, Gokhan; Bilge, S. Sirri (Elsevier Ireland Ltd, 2020)The transient receptor potential ankyrin 1 (TRPA1), a member of the TRP superfamily, is widely distributed in the central nervous system (CNS) and plays an important role in pain and inflammation. However, no data has been ... -
Resveratrol Enhances Apoptotic and Oxidant Effects of Paclitaxel through TRPM2 Channel Activation in DBTRG Glioblastoma Cells
Ozturk, Yasin; Gunaydin, Caner; Yalcin, Fatma; Naziroglu, Mustafa; Braidy, Nady (Hindawi Ltd, 2019)Numerous studies have reported a strong association between increased production of reactive oxygen species (ROS) and the pathobiology of several diseases, and cancer in particular. Therefore, manipulation of cellular ... -
The role of muscarinic and serotonergic-2A receptors in the antinociceptive effect of pregabalin
Hallak, Mohamad; Balci, Hakan; Gunaydin, Caner; Bilge, S. Sirri (Iranian Soc Physiology & Pharmacology, 2019)Introduction: Pregabalin (PGB) is an analog of gamma-aminobutyric acid (GABA) with antinociceptive, antihyperalgesic and antiallodynic properties which frequently used in clinical pain management. Effect of PBG in neuropathic ...
