Yazar "Guney, Murat" için listeleme
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Biological Evaluation of Some Uracil Derivatives as Potent Glutathione Reductase Inhibitors
Guney, Murat; Ekinci, Deniz; Cavdar, Huseyin; Senturk, Murat; Zilbeyaz, Kani (Amer Inst Physics, 2016)Discovery of glutathione reductase (GR) inhibitors has become very popular recently due to antimalarial and anticancer activities. In this study, GR inhibitory capacities of some uracil derivatives (UDCs) (1-4) were reported. ... -
Inhibition of acetylcholinesterase and butyrylcholinesterase with uracil derivatives: kinetic and computational studies
Cavdar, Huseyin; Senturk, Murat; Guney, Murat; Durdagi, Serdar; Kayik, Gulru; Supuran, Claudiu T.; Ekinci, Deniz (Taylor & Francis Ltd, 2019)Acetylcholinesterase (AChE) and Butyrylcholinesterase (BuChE) inhibitors are interesting compounds for different therapeutic applications, among which Alzheimer's disease. Here, we investigated the inhibition of these ... -
Synthesis and carbonic anhydrase inhibitory properties of novel uracil derivatives
Guney, Murat; Cavdar, Huseyin; Senturk, Murat; Ekinci, Deniz (Pergamon-Elsevier Science Ltd, 2015)Carbonic anhydrase (CA) inhibitors are valuable molecules based on several therapeutic applications, including antiglaucoma activity. In the present study, inhibition of two human cytosolic carbonic anhydrase isozymes I ...
