Browsing by Author "Kaur, Simarjot"

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Borrelia burgdorferi BBI39 Paralogs, Targets of Protective Immunity, Reduce Pathogen Persistence Either in Hosts or in the Vector

Singh, Preeti; Verma, Deepshikha; Backstedt, Brian T.; Kaur, Simarjot; Kumar, Manish; Smith, Alexis A.; Pal, Utpal (Oxford Univ Press Inc, 2017)

Borrelia burgdorferi genome harbors several paralogous gene families (pgf) that can encode immunogenic proteins of unknown function. Protein-protein interaction assays using a transmission-blocking vaccine candidate, BBA52, ...
A Borrelia burgdorferi Surface-Exposed Transmembrane Protein Lacking Detectable Immune Responses Supports Pathogen Persistence and Constitutes a Vaccine Target

Kung, Faith; Kaur, Simarjot; Smith, Alexis A.; Yang, Xiuli; Wilder, Cara N.; Sharma, Kavita; Pal, Utpal (Oxford Univ Press Inc, 2016)

Borrelia burgdorferi harbors a limited set of transmembrane surface proteins, most of which constitute key targets of humoral immune responses. Here we show that BB0405, a conserved membrane-spanning protein of unknown ...