Yazar "Kurt-Kizildogan, Aslihan" için listeleme
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Design, Synthesis, and in vitro Evaluation of Thieno[a]dibenzothiophene Derivatives
Konus, Metin; Algso, Muheb A. S.; Kavak, Emrah; Kurt-Kizildogan, Aslihan; Yilmaz, Can; Kivrak, Arif (Wiley-V C H Verlag Gmbh, 2020)A variety of highly substituted thieno[2,3-a]dibenzothiophenes and thieno[3,2-a]dibenzothiophenes are readily prepared via cascade electrophilic cyclization reaction. The reaction was tolerated a variety of compounds. In ... -
Highly active and stable protease production by an extreme halophilic archaeon Haloarcula sp TG1 isolated from Lake Tuz, Turkey
Abanoz, Busra; Okay, Sezer; Kurt-Kizildogan, Aslihan (Walter De Gruyter Gmbh, 2017)Objective: Isolation of halophilic microorganisms from Cankiri salt mine and Lake Tuz in Turkey to explore versatile protease producers for industry and characterization of protease enzyme from the best protease producer ... -
Homologous expression of lysA encoding diaminopimelic acid (DAP) decarboxylase reveals increased antibiotic production in Streptomyces clavuligerus
Otur, Cigdem; Kurt-Kizildogan, Aslihan (Springer, 2020)lysA gene encoding meso-diaminopimelic acid (DAP) decarboxylase enzyme that catalyzes l-lysine biosynthesis in the aspartate pathway in Streptomyces clavuligerus was overexpressed, and its effects on cephamycin C (CephC), ... -
Molecular and biochemical characterization of a recombinant endoglucanase rCKT3eng, from an extreme halophilic Haloarcula sp. strain CKT3
Safak, Haktan; Otur, Cigdem; Kurt-Kizildogan, Aslihan (Elsevier, 2020)Halophilic cellulases are indispensable enzymes of heavy industrial processes as resistant biocatalysts due to high level activity at extreme conditions. In this study, crude cellulase from an extreme halophilic Haloatrula ... -
Proteome-wide alterations in an industrial clavulanic acid producing strain of Streptomyces clavuligerus
Unsaldi, Eser; Kurt-Kizildogan, Aslihan; Voigt, Birgit; Becher, Doerte; Ozcengiz, Gulay (Keai Publishing Ltd, 2017)The usefulness of genetic/metabolic engineering for further improvement of industrial strains is subject of discussion because of the general lack of knowledge on genetic alterations introduced by iterative cycles of random ... -
Synthesis and biological evaluation of novel benzothiophene derivatives
Algso, Muheb A. S.; Kivrak, Arif; Konus, Metin; Yilmaz, Can; Kurt-Kizildogan, Aslihan (Indian Acad Sciences, 2018)Benzothiophene derivatives were synthesized regioselectively using coupling reactions and electrophilic cyclization reactions. Antimicrobial properties of isolated compounds were tested against indicator microorganisms ... -
Synthesis, Biological Evaluation and Molecular Docking of Novel Thiophene-Based Indole Derivatives as Potential Antibacterial, GST Inhibitor and Apoptotic Anticancer Agents
Konus, Metin; Cetin, Dogan; Yilmaz, Can; Arslan, Sevki; Mutlu, Dogukan; Kurt-Kizildogan, Aslihan; Kivrak, Arif (Wiley-V C H Verlag Gmbh, 2020)Heteroaromatic indoles play a leading role in the development of pharmaceutical, medical, chemical and agricultural fields due to their structural properties. In this study, it was first time that biological properties of ...
