Yazar "Mahmutoglu, Asli Metin" için listeleme
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Genetic and epigenetic effects in sex determination
Gunes, Sezgin Ozgur; Mahmutoglu, Asli Metin; Agarwal, Ashok (Wiley, 2016)Sex determination is a complex and dynamic process with multiple genetic and environmental causes, in which germ and somatic cells receive various sex-specific features. During the fifth week of fetal life, the bipotential ... -
Smoking-induced genetic and epigenetic alterations in infertile men
Gunes, Sezgin; Mahmutoglu, Asli Metin; Arslan, Mehmet Alper; Henkel, Ralf (Wiley, 2018)Male fertility rates have shown a progressive decrease in both developing and industrialised countries in the past 50years. Clinical and epidemiological studies have demonstrated controversial results about the harmful ... -
SNP's in xenobiotic metabolism and male infertility
Hekim, Neslihan; Gure, Mohamed Ali; Mahmutoglu, Asli Metin; Gunes, Sezgin; Asci, Ramazan; Henkel, Ralf (Taylor & Francis Ltd, 2020)1. Glutathione S-transferases (GST) and cytochrome P450s (CYPs) are xenobiotic metabolizing enzymes participating in the protection of cell. The present study aimed to investigate the relationship between polymorphisms of ...