Yazar "Steinbusch, Harry W. M." için listeleme
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Bilateral high frequency stimulation of the subthalamic nucleus normalizes COX activity in the substantia nigra of Parkinsonian rats
Vlamings, Rinske; Visser-Vandewalle, Veerle; Kozan, Ramazan; Kaplan, Süleyman; Steinbusch, Harry W. M.; Temel, Yasin (Elsevier Science Bv, 2009)Part of the mechanism underlying the therapeutic effect of subthalamic nucleus (STN) high frequency stimulation (HFS) involves the activity of the basal ganglia output structures. The general idea is that STN's burst ... -
Electrical stimulation of the motor cortex enhances progenitor cell migration in the adult rat brain
Jahanshahi, Ali; Schonfeld, Lisa; Janssen, Marcus L. F.; Hescham, Sarah; Kocabicak, Ersoy; Steinbusch, Harry W. M.; Temel, Yasin (Springer, 2013)Clinical and preclinical investigations suggest that epidural stimulation of the motor cortex (MC) can improve stroke-induced neurological deficits. The mechanisms involved in stimulation-induced recovery are not well ... -
Increased electrical and metabolic activity in the dorsal raphe nucleus of Parkinsonian rats
Kaya, Ahmet H.; Vlamings, Rinske; Tan, Sonny; Lim, Lee Wei; Magill, Peter J.; Steinbusch, Harry W. M.; Temel, Yasin (Elsevier Science Bv, 2008)Serotonin (5-HT) containing neurons in the dorsal raphe nucleus (DRN) may play important roles in Parkinson's disease (PD). This study investigated neural and metabolic activity of the DRN in animal PD models based on ... -
Protection of nigral cell death by bilateral subthalamic nucleus stimulation
Temel, Yasin; Visser-Vandewalle, Veerle; Kaplan, Süleyman; Kozan, Ramazan; Daemen, Marc A. R. C.; Blokland, Arjan; Steinbusch, Harry W. M. (Elsevier Science Bv, 2006)In Parkinson disease (PD), the subthalamic nucleus (STN) becomes hyperactive (disinhibited), which is reported to cause excitotoxic damage to midbrain dopaminergic neurons. Here, we examined whether silencing of the ...
