Yazar "Vlamings, Rinske" için listeleme
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Bilateral high frequency stimulation of the subthalamic nucleus normalizes COX activity in the substantia nigra of Parkinsonian rats
Vlamings, Rinske; Visser-Vandewalle, Veerle; Kozan, Ramazan; Kaplan, Süleyman; Steinbusch, Harry W. M.; Temel, Yasin (Elsevier Science Bv, 2009)Part of the mechanism underlying the therapeutic effect of subthalamic nucleus (STN) high frequency stimulation (HFS) involves the activity of the basal ganglia output structures. The general idea is that STN's burst ... -
Hyperdopaminergic Status in Experimental Huntington Disease
Jahanshahi, Ali; Vlamings, Rinske; Kaya, Ahmet Hilmi; Lim, Lee Wei; Janssen, Marcus L. F.; Tan, Sonny; Temel, Yasin (Oxford Univ Press Inc, 2010)Huntington disease has been linked to increased dopaminergic neurotransmission in the striatum, and clinical studies have demonstrated that the associated chorea can be treated with dopamine antagonist or dopamine-depleting ... -
Increased electrical and metabolic activity in the dorsal raphe nucleus of Parkinsonian rats
Kaya, Ahmet H.; Vlamings, Rinske; Tan, Sonny; Lim, Lee Wei; Magill, Peter J.; Steinbusch, Harry W. M.; Temel, Yasin (Elsevier Science Bv, 2008)Serotonin (5-HT) containing neurons in the dorsal raphe nucleus (DRN) may play important roles in Parkinson's disease (PD). This study investigated neural and metabolic activity of the DRN in animal PD models based on ... -
Transgenic Rat Models of Huntington's Disease
Carreira, Joao Casaca; Jahanshahi, Ali; Zeef, Dagmar; Kocabicak, Ersoy; Vlamings, Rinske; von Hoersten, Stephan; Temel, Yasin (Springer International Publishing Ag, 2015)Several animal models for Huntington's disease (HD) have been created in order to investigate mechanisms of disease, and to evaluate the potency of novel therapies. Here, we describe the characteristics of the two transgenic ...