Yazar "Yildirim, Tuba" için listeleme
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Biological Activity of New Cyclophosphazene Derivatives Including Fluorenylidene-Bridged Cyclophosphazenes
Yildirim, Tuba; Senkuytu, Elif; Ergene, Emel; Bilgin, Kemal; Uludag, Yildiz; Ciftci, Gonul Yenilmez (Wiley-V C H Verlag Gmbh, 2018)In this study, new cyclophosphazene compounds were synthesized characterized and their biological activity studies were performed. The structural investigations of the compounds were verified by elemental analyses, mass ... -
Determination of PER-1 and OXA-10-like beta-lactamases in Ceftazidime-Resistant Pseudomonas aeruginosa Isolates by Molecular Methods
Sogut, Mehtap Unlu; Yildirim, Tuba; Birinci, Asuman; Durupinar, Belma (Ortadogu Ad Pres & Publ Co, 2011)Objective: Pseudomonas aeruginosa is one of the important nosocomial pathogens and resistant to many antibiotics including beta-lactams. PER-1 and OXA-10 type extended-spectrum beta-lactamases (ESBLs), the major beta-lactamases, ... -
Generation of Mouse Hybridomas Secreting Anti-Salmonella Enteritidis Antibodies and Their Preliminary Characterization
Buyuktanir, Ozlem; Yagci, Tamer; Findik, Arzu; Yildirim, Tuba; Yurdusev, Nevzat (Kafkas Univ, Veteriner Fakultesi Dergisi, 2011)BALB/c mice were intraperitoneally immunized with inactivated bacteria for generation of monoclonal anti-S. Enteritidis antibody. The spleen cells of the highest responder animal at fifth immunization were used as the ... -
Investigation of Plasmid-Mediated Quinolone Resistance in Pseudomonas aeruginosa Strains Isolated from Cystic Fibrosis Patients
Coban, Ahmet Yilmaz; Cayci, Yeliz Tanriverdi; Yildirim, Tuba; Erturan, Zayre; Durupinar, Belma; Bozdogan, Bulent (Ankara Microbiology Soc, 2011)Pseudomonas aeruginosa which is widely found in the environment, may lead to serious nosocomial infections. Due to its intrinsic resistance to many antibacterial agents, treatment of P.aeruginosa infections usually present ... -
Investigation of the relationship between class-1 integrons and per-1 enzyme in ceftazidime resistant Pseudomonas aeruginosa
Opus, Aysegul; Yildirim, Tuba; Birinci, Asuman; Durupinar, Belma (Scientific Publishers India, 2017)Pseudomonas aeruginosa strains, especially multidrug resistant, have great of importance among nosocomial infection isolates. Production of beta lactamase is an important mechanism in gram-negative bacteria for resistance ... -
Molecular typing of Staphylococcus aureus strains from ovine mastitis by pulsed-field gel electrophoresis and polymerase chain reaction based on coagulase and protein A gene polymorphisms
Ciftci, Alper; Onuk, E. Emek; Findik, Arzu; Yildirim, Tuba; Sogut, Mehtap Unlu (Sage Publications Inc, 2009)Slaphylococcus aureus is one of the most important etiologic agents of ovine mastitis. To develop effective control measures for mastitis, it is important to type S. aureus strains that have considerable genetic heterogeneity. ... -
Prevalence and Characterization of Coagulase Positive Staphylococci Isolated from Salted Anchovy
Siriken, Belgin; Yildirim, Tuba; Erol, Irfan; Durupinar, Belma; Ciftci, Alper; Onuk, Ertan Emek (Taylor & Francis Inc, 2013)A total of 100 salted anchovy samples were used to investigate the prevalence of S. aureus and other coagulase positive Staphylococci (CPS) as well as to determine the methicillin (MR) and antibiotic resistance (AR) profile, ... -
Prevalence and Characterization of Salmonella Isolated from Chicken Meat in Turkey
Siriken, Belgin; Turk, Haldun; Yildirim, Tuba; Durupinar, Belma; Erol, Irfan (Wiley, 2015)This study was conducted in a Turkish province to investigate the presence of Salmonella spp. in 150 chicken meat samples using 2 phenotyping techniques: classic culture technique (CCT) and immunomagnetic separation (IMS). ... -
Prevalence and Molecular Characterization of Methicillin-Resistant Staphylococcus aureus in Foods of Animal Origin, Turkey
Siriken, Belgin; Yildirim, Tuba; Guney, Akif Koray; Erol, Irfan; Durupinar, Belma (Int Assoc Food Protection, 2016)In the present study, 175 coagulase-positive Staphylococcus (CPS) isolates recovered from samples of beef (n = 110), raw milk n 56), and fish (n = 9) were analyzed for methicillin resistance using MIC and PCR assays. ... -
Rapid detection of methicillin resistance in Staphylococcus aureus isolates; evaluation of colorimetric Quicolor ES agar and determination of breakpoint inhibition zone diameters of cefoxitin
Coban, Ahmet Yilmaz; Demirpek, Ugur; Yildirim, Tuba; Cayci, Yeliz Tanriverdi; Kocagoz, Tanil; Durupinar, Belma (Springer, 2011)In this study, it was aimed to evaluate colorimetric Quicolor ES agar for the rapid detection of methicillin resistance and to determine susceptibility and resistance breakpoint zone diameters for cefoxitin by using 51 ... -
A recombinant PvpA protein-based diagnostic prototype for rapid screening of chicken Mycoplasma gallisepticum infections
Bueyuektanir, Ozlem; Yildirim, Tuba; Yakicier, Cengiz; Genc, Oktay; Yurdusev, Nevzat (Elsevier Science Bv, 2008)Mycoplasma gallisepticum is the primary agent of chronic respiratory disease causing important economic losses in the poultry industry. Serological monitoring is essential to maintain mycoplasma-free breeder flocks and ... -
Synthesis and characterization of new cyclotriphosphazene compounds
Ciftci, Gonul Yenilmez; Ecik, Esra Tannverdi; Yildirim, Tuba; Bilgin, Kemal; Senkuytu, Elif; Yuksel, Fatma; Kilic, Adem (Pergamon-Elsevier Science Ltd, 2013)In the present study, Spiro (1a), dispiro (1b, 2, 3), per-substituted spermine-bridged (6-9) and dispiroansa spermine (10) derivatives of cyclotriphosphazene have been synthesized. The structures of the novel compounds ... -
Synthesis, cytotoxicity and apoptosis of cyclotriphosphazene compounds as anti-cancer agents
Yildirim, Tuba; Bilgin, Kemal; Ciftci, Gonul Yenilmez; Ecik, Esra Tanriverdi; Senkuytu, Elif; Uludag, Yildiz; Kilic, Adem (Elsevier France-Editions Scientifiques Medicales Elsevier, 2012)In the present study, a number of new dispirobino and dispiroansa spermine derivatives of cyclotriphosphazene (8-10, 13) were synthesized and characterized by elemental analysis, mass spectrometry, H-1 and P-31 NMR ...