Basit öğe kaydını göster

dc.contributor.authorCelik, B.
dc.contributor.authorAydin, O.
dc.contributor.authorCilingir, A.
dc.contributor.authorBasoglu, A.
dc.date.accessioned2020-06-21T15:07:07Z
dc.date.available2020-06-21T15:07:07Z
dc.date.issued2009
dc.identifier.issn0171-6425
dc.identifier.issn1439-1902
dc.identifier.urihttps://doi.org/10.1055/s-2008-1039103
dc.identifier.urihttps://hdl.handle.net/20.500.12712/18770
dc.descriptionWOS: 000264542500007en_US
dc.descriptionPubMed: 19241312en_US
dc.description.abstractBackground: Aim of the study was to compare the pleurodesis results from the intrapleural injection of talc, polidocanol and ethanol into the rabbit pleura. Methods: Twenty-nine New Zealand white rabbits were randomized into three groups for the intrapleural administration of 200 mg/kg (n = 10) of talc, 15 mg/kg (n = 10) of 3 % polidocanol or 1 mL (n = 9) of 4.2% ethanol in 2 mL saline solution, respectively. The pleural spaces were assessed grossly for evidence of pleurodesis and microscopically for evidence of inflammation, thickness, cellularity, neovascularity and mesothelial cell proliferation in both pleura. Results: The mean degrees of gross pleurodesis were 2.0 +/- 0.66 (on a scale from 0 to 4) for talc, 2.2 +/- 0.91 for polidocanol and 0.7 +/- 0.86 for ethanol. The parietal pleura thickness was 191 213.6 mu m 236 +/-224.6 mu m and 45 +/- 44.2 mu m, while the visceral pleura thickness was 109 +/-103.7 mu m, 164 +/- 161.4 mu m and 48 +/- 42.2 mu m in the talc, polidocanol and ethanol groups, respectively. The results of microscopic examination were similar in the talc and polidocanol groups. Conclusion: The intrapleural injection of polidocanol produces better pleurodesis than does the intrapleural injection of talc or ethanol in rabbits. Because of the efficacy of polidocanol as a sclerosing agent, its use in humans should be considered after further animal studies.en_US
dc.language.isoengen_US
dc.publisherGeorg Thieme Verlag Kgen_US
dc.relation.isversionof10.1055/s-2008-1039103en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectpleurodesisen_US
dc.subjecttalcen_US
dc.subjectpolidocanolen_US
dc.subjectpleuraen_US
dc.titleA Comparison of the Effectiveness of Talc, Polidocanol and Ethanol as Pleural Sclerosing Agents in Rabbitsen_US
dc.typearticleen_US
dc.contributor.departmentOMÜen_US
dc.identifier.volume57en_US
dc.identifier.issue2en_US
dc.identifier.startpage102en_US
dc.identifier.endpage106en_US
dc.relation.journalThoracic and Cardiovascular Surgeonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


Bu öğenin dosyaları:

DosyalarBoyutBiçimGöster

Bu öğe ile ilişkili dosya yok.

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster