Genetics of prostate cancer

Abstract

Prostate cancer is the most common malignancy among men in Weastern industrialized countries. Despite its high incidence, the molecular and genetic events involved in progression of prostate cancer remain poorly understood. Epidemiological studies have suggested that 5-10% of all prostate cancers are familial, and numerous chromosomal loci have been associated with prostate cancer. This paper describes the genetic alterations in prostate tumorogenesis.