A comparison between the effects of calcipotriol lotion, momethasone furoate lotion and their combinations for the treatment of scalp psoriasis

Abstract

Background: Topical corticosteroids and calcipotriol lotion are the most preferred agents for the treatment of scalp psoriasis. Since combination treatments increase effectiveness and decrease side effects, they are usually preferred for treatment of scalp psoriasis. The aim of our study was to compare the effectiveness and side effects of momethasone furoate lotion, calcipotriol lotion and combination of these two agents for the scalp psoriasis. Materials and Methods: Forty-five patients who had mild to moderate scalp psoriasis were randomly divided to three groups. Calcipotriol lotion for the first group, momethasone furoate lotion for the second group and combination of these two agents for the third group were used for four weeks. Results: At the end of the study extent score, itching score, total clinical sign score and psoriasis scalp seventy index were found to be decreased in all of the groups (p<0.05). Less side effects were observed in the third group who used combination therapy compared to the calcipotriol group. Conclusion: Although momethasone furoate lotion and calcipotriol lotion were both effective for scalp psoriasis, combination of these agents was more effective and caused less side effects.