Comparing the effects of levobupivacaine and bupivacaine used in spinal anesthesia for elective cesarean section

Abstract

Objective: We aimed to compare the effect of bupivacaine and levobupivacaine which are intrathecally used during the elective cesarean section under spinal anesthesia. Material and Method: Eighty patients were included in the study groups who were managed with a cesarean section under spinal anesthesia. Randomly selected fourty pregnant were administered with 12.5 mg bupivacaine+20 ?g fentanyl and the other 40 pregnant were administered with 12.5 mg levobupivacaine+20 ?g fentanyl. The basal heart rate and arterial pressure values were preoperatively obtained. These values were recorded by one minute intenals till the baby came out and then measured by 3 minutes interval. After the 20 minutes, measurements were recorded by 5 minutes interval till the block level regressed to T10. Additionally, sensorial and motor block, satisfaction of patient and surgeon, and analgesia quality were evaluated. Results: The Bromage scores at first minute in the levobupivacaine group were significantly lower compared with the bupivacaine group's (p<0.05). The analgesia period was significantly longer in the levobupivacaine group than the bupivacaine group (p<0.05). The hypotension incidence in the bupivacaine group was significantly higher than levobupivacaine group's (p<0.05). There was no statistical significance in the apgar score, heart rate, sistolic, and diastolic values of groups (p>0.05). Conclusion: Levobupivacaine is a good alternative for bupivacaine in equal doses during the cesarean section under the spinal anesthesia.