Valproic acid-induced neutropenia

Abstract

Valproic acid is an important anticonvulsant agent but it has some serious side effects. Neutropenia is one of them. A one-year old female patient applied to our hospital for control. Neutropenia was determined in her complete blood count. She was given some specific diagnostic tests to explain the cause of neutropenia. At the end of the evaluation, it was thought that neutropenia was due to valproate. The patient's hematological parameters improved after stopping drug apply. This case was found interesting enough to be presented since VPA-induced neutropenia had caused fever.