A case-control study on the etiology of urinary bladder cancer in Istanbul, Turkey

Abstract

Background: Urinary bladder cancer is the third leading cancer in male in Turkey. The incidence rates of bladder cancer are 13.0 and 2.1/ 100,000 for males and females, respectively, in Turkey. Smoking and occupation are the main causes of urinary bladder cancer. Our goal was to investigate the etiologic factors of urinary bladder cancer in our region to improve our preventive services. Methods: We conducted a hospital-based case-control study of patients with bladder cancer and of controls drawn randomly from the acute non-urinary patients of three hospitals in Istanbul. Controls were matched for age, sex, and residence. Results: We interviewed 290 cases and 580 controls. Smoking and occupation were found to be related factors in urinary bladder cancer. Conclusion: Preventive measures should be planned regarding smoking and occupational factors for urinary bladder cancer in Turkey.