Results of amniocentesis cytogenetic analysis between 2000 and 2005 years at Samsun and around

Abstract

In this study, we aimed to present of the results cytogenetic analysis and amniocentesis indications between the years 2000 and 2005 at Samsun and around. In this study 530 pregnancies were investigated. Each patient had one of the amniocentesis indications such as high biochemical risk (?1/250), mother age (?35), genetic disease in the family history, abnormal ultrasonography findings, and combination of indications given above. Amnion samples were analyzed with conventional cytogenetic methods in weeks 16-20 of conceptions. Average age of mothers in the study was 34.6 years old. Amnion samples chromosome analyses, showed 2.7% anomalies. These are 0.9% classic trisomy 21, 0.2% mosaic, 0.8% balanced translocations, and 0.8% pericentric inversions.