Voltammetric and spectroscopic studies of vanadium (V)-nicotinamide interactions at physiological pH

Abstract

The interaction of nicotinamide (NA) with NH4VO3 at the physiological pH (pH 7.4) was studied by voltammetry and UV-Vis spectroscopy. The reduction of V(V) ions complexed with NA in phosphate buffer (pH 7.4) was observed as a well-defined reversible reduction peak at -0.35 V. The stoichiometric (metahligand) ratio of the complex of V(V) with NA was determined as 1:2 by the mole ratio method.