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Paraoxonase-1, an organophosphate detoxifier and cardioprotective enzyme, is inhibited by anesthetics: An in vitro and in vivo insight

Senturk, Murat; Ekinci, Deniz; Alici, Haci Ahmet; Beydemir, Sukru (Academic Press Inc Elsevier Science, 2011)

Paraoxonase-1 enzyme (PON1) is important in metabolism as an organophosphate (OP) hydrolyser, hydrolyses aromatic carboxyl esters, such as phenyl acetate, and is involved in drug and xenobiotic metabolism. Moreover, it ...